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NUP54 Antibody

Product Specifications

Background

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. NUP54 is a member of the phe-gly (FG) repeat-containing nucleoporin subset.

NCBI Gene ID

53371

Swiss Prot

Q7Z3B4

Accession Number

Q7Z3B4

Host

Rabbit

Reactivity

Human

Immunogen

This NUP54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-243 amino acids from the Central region of human NUP54.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NUP54

NCBI Official Name

Nucleoporin p54

NCBI Organism

Homo sapiens

Background Reference 01

Stoffler, D., et al., Curr. Opin. Cell Biol. 11 (3) :391-401 (1999) .

Background Reference 02

Bodoor, K., et al., Biochem. Cell Biol. 77 (4) :321-329 (1999) .

Background Reference 03

Popov, S., et al., J. Biol. Chem. 273 (21) :13347-13352 (1998) .

Background Reference 04

Hu, T., et al., J. Cell Biol. 134 (3) :589-601 (1996) .

Other Product Names

Nucleoporin p54, 54 kDa nucleoporin, NUP54

Tested Applications

WB

Physical Properties

Liquid

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