NUP54 Antibody
Product Specifications
Background
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. NUP54 is a member of the phe-gly (FG) repeat-containing nucleoporin subset.
NCBI Gene ID
53371
Swiss Prot
Q7Z3B4
Accession Number
Q7Z3B4
Host
Rabbit
Reactivity
Human
Immunogen
This NUP54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-243 amino acids from the Central region of human NUP54.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NUP54
NCBI Official Name
Nucleoporin p54
NCBI Organism
Homo sapiens
Background Reference 01
Stoffler, D., et al., Curr. Opin. Cell Biol. 11 (3) :391-401 (1999) .
Background Reference 02
Bodoor, K., et al., Biochem. Cell Biol. 77 (4) :321-329 (1999) .
Background Reference 03
Popov, S., et al., J. Biol. Chem. 273 (21) :13347-13352 (1998) .
Background Reference 04
Hu, T., et al., J. Cell Biol. 134 (3) :589-601 (1996) .
Other Product Names
Nucleoporin p54, 54 kDa nucleoporin, NUP54
Tested Applications
WB
Physical Properties
Liquid
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