Reptin/TIP49B/RUVB2 Antibody
Product Specifications
Background
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
NCBI Gene ID
10856
Swiss Prot
Q9Y230
Accession Number
Q9Y230
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Reptin/TIP49B/RUVB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-430 amino acids from the C-terminal region of human Reptin/TIP49B/RUVB2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Xenopus, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RUVBL2
NCBI Official Name
RuvB-like 2
NCBI Organism
Homo sapiens
Background Reference 01
Bauer, A., et al., EMBO J. 19 (22) :6121-6130 (2000) .
Background Reference 02
Parfait, B., et al., Ann. Genet. 43 (2) :69-74 (2000) .
Background Reference 03
Wood, M.A., et al., Mol. Cell 5 (2) :321-330 (2000) .
Background Reference 04
Salzer, U., et al., Biochim. Biophys. Acta 1446 (3) :365-370 (1999) .
Other Product Names
RuvB-like 2, 48 kDa TATA box-binding protein-interacting protein, 48 kDa TBP-interacting protein, 51 kDa erythrocyte cytosolic protein, ECP-51, INO80 complex subunit J, Repressing pontin 52, Reptin 52, TIP49b, TIP60-associated protein 54-beta, TAP54-beta, RUVBL2, INO80J, TIP48, TIP49B
Tested Applications
WB
Protein ID
28201890
Physical Properties
Liquid
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