Reptin/TIP49B/RUVB2 Antibody

Product Specifications

Background

This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

NCBI Gene ID

10856

Swiss Prot

Q9Y230

Accession Number

Q9Y230

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Reptin/TIP49B/RUVB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-430 amino acids from the C-terminal region of human Reptin/TIP49B/RUVB2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Xenopus, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RUVBL2

NCBI Official Name

RuvB-like 2

NCBI Organism

Homo sapiens

Background Reference 01

Bauer, A., et al., EMBO J. 19 (22) :6121-6130 (2000) .

Background Reference 02

Parfait, B., et al., Ann. Genet. 43 (2) :69-74 (2000) .

Background Reference 03

Wood, M.A., et al., Mol. Cell 5 (2) :321-330 (2000) .

Background Reference 04

Salzer, U., et al., Biochim. Biophys. Acta 1446 (3) :365-370 (1999) .

Other Product Names

RuvB-like 2, 48 kDa TATA box-binding protein-interacting protein, 48 kDa TBP-interacting protein, 51 kDa erythrocyte cytosolic protein, ECP-51, INO80 complex subunit J, Repressing pontin 52, Reptin 52, TIP49b, TIP60-associated protein 54-beta, TAP54-beta, RUVBL2, INO80J, TIP48, TIP49B