Mouse Nod1 Antibody

Product Specifications

Background

Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS) . Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens (By similarity) .

NCBI Gene ID

107607

Swiss Prot

Q8BHB0

Accession Number

Q8BHB0

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Nod1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-584 amino acids from the Central region of mouse Nod1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Inflammasomes

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

108 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Nod1

NCBI Official Name

Nucleotide-binding oligomerization domain-containing protein 1

NCBI Organism

Mus musculus

Background Reference 01

Moreno, L., et al. Br. J. Pharmacol. 160 (8) :1997-2007 (2010)

Background Reference 02

Iyer, J.K., et al. Infect. Immun. 78 (6) :2418-2428 (2010)

Background Reference 03

Watanabe, T., et al. J. Clin. Invest. 120 (5) :1645-1662 (2010)

Background Reference 04

Toma, C., et al. J. Immunol. 184 (9) :5287-5297 (2010)

Other Product Names

Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, Nod1, Card4

Tested Applications

Physical Properties

Liquid

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