SNAPC3 Antibody

Product Specifications

Background

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

NCBI Gene ID

6619

Swiss Prot

Q92966

Accession Number

Q92966

Host

Rabbit

Reactivity

Human

Immunogen

This SNAPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human SNAPC3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SNAPC3

NCBI Official Name

SnRNA-activating protein complex subunit 3

NCBI Organism

Homo sapiens

Background Reference 01

Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

Background Reference 02

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Background Reference 03

Jawdekar, G.W., et al. J. Biol. Chem. 281 (41) :31050-31060 (2006)

Background Reference 04

Humphray, S.J., et al. Nature 429 (6990) :369-374 (2004)

Other Product Names

SnRNA-activating protein complex subunit 3, SNAPc subunit 3, Proximal sequence element-binding transcription factor subunit beta, PSE-binding factor subunit beta, PTF subunit beta, Small nuclear RNA-activating complex polypeptide 3, snRNA-activating protein complex 50 kDa subunit, SNAPc 50 kDa subunit, SNAPC3, SNAP50