SIRPB2 Antibody

Product Specifications

Background

Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.

NCBI Gene ID

284759

Swiss Prot

Q5JXA9

Accession Number

Q5JXA9

Host

Rabbit

Reactivity

Human

Immunogen

This SIRPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-255 amino acids from the C-terminal region of human SIRPB2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SIRPB2

NCBI Official Name

Signal-regulatory protein beta-2

NCBI Organism

Homo sapiens

Background Reference 01

Nyati, M.K., et al. Cancer Res. 66 (24) :11554-11559 (2006)

Background Reference 02

Van den Berg, T.K., et al. J. Immunol. 175 (12) :7788-7789 (2005)

Background Reference 03

Chen, J., et al. Proc. Natl. Acad. Sci. U.S.A. 99 (19) :12257-12262 (2002)

Other Product Names

Signal-regulatory protein beta-2, SIRP-beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein, SIRPB2, PTPN1L, PTPNS1L3