What is the catalog number for Elongin A Antibody?

The catalog number for Elongin A Antibody is 60-375.

What sizes are available for Elongin A Antibody?

Elongin A Antibody is available in the following size(s): 400 µL.

Is Elongin A Antibody in stock?

Elongin A Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Elongin A Antibody

Product Specifications

Background

Elongin A is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

NCBI Gene ID

6924

Swiss Prot

Q14241

Accession Number

Q14241

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Elongin A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-127 amino acids from the N-terminal region of human Elongin A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

90 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TCEB3

NCBI Official Name

Transcription elongation factor B polypeptide 3

NCBI Organism

Homo sapiens

Background Reference 01

Beausoleil, S.A., et al., Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004) .

Background Reference 02

Tamura, K., et al., Biochem. Biophys. Res. Commun. 309 (1) :189-195 (2003) .

Background Reference 03

Kile, B.T., et al., Trends Biochem. Sci. 27 (5) :235-241 (2002) .

Background Reference 04

Yamazaki, K., et al., J. Biol. Chem. 277 (29) :26444-26451 (2002) .

Other Product Names

Transcription elongation factor B polypeptide 3, Elongin 110 kDa subunit, Elongin-A, EloA, RNA polymerase II transcription factor SIII subunit A1, SIII p110, TCEB3