PANX2 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

56666

Swiss Prot

Q96RD6

Accession Number

Q96RD6

Host

Rabbit

Reactivity

Human

Immunogen

This PANX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the C-terminal region of human PANX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

74 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PANX2

NCBI Official Name

Pannexin-2

NCBI Organism

Homo sapiens

Background Reference 01

Ambrosi, C., et al. J. Biol. Chem. 285 (32) :24420-24431 (2010)

Background Reference 02

Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)

Background Reference 03

Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)

Background Reference 04

Lai, C.P., et al. Oncogene 28 (49) :4402-4408 (2009)

Other Product Names

Pannexin-2, PANX2

Tested Applications

Protein ID

296439257

Physical Properties

Liquid

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