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FGD3 Antibody

Product Specifications

Background

FGD3 promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity) .

NCBI Gene ID

89846

Swiss Prot

Q5JSP0

Accession Number

Q5JSP0

Host

Rabbit

Reactivity

Human

Immunogen

This FGD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-601 amino acids from the C-terminal region of human FGD3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

79 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FGD3

NCBI Official Name

FYVE, RhoGEF and PH domain-containing protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Delague, V., et al. Am. J. Hum. Genet. 81 (1) :1-16 (2007)

Background Reference 03

Humphray, S.J., et al. Nature 429 (6990) :369-374 (2004)

Background Reference 04

Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :

Other Product Names

FYVE, RhoGEF and PH domain-containing protein 3, Zinc finger FYVE domain-containing protein 5, FGD3, ZFYVE5

Tested Applications

WB

Protein ID

61213216

Physical Properties

Liquid

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