UBASH3A Antibody

Product Specifications

Background

UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.

NCBI Gene ID

53347

Swiss Prot

P57075

Accession Number

P57075

Host

Rabbit

Reactivity

Mouse

Immunogen

This UBASH3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human UBASH3A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

74 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UBASH3A

NCBI Official Name

Ubiquitin-associated and SH3 domain-containing protein A

NCBI Organism

Homo sapiens

Background Reference 01

Hinks, A., et al. Ann. Rheum. Dis. (2010) In press :

Background Reference 02

Stahl, E.A., et al. Nat. Genet. 42 (6) :508-514 (2010)

Background Reference 03

Jin, Y., et al. N. Engl. J. Med. 362 (18) :1686-1697 (2010)

Background Reference 04

Barrett, J.C., et al. Nat. Genet. 41 (6) :703-707 (2009)

Other Product Names

Ubiquitin-associated and SH3 domain-containing protein A, Cbl-interacting protein 4, CLIP4, Suppressor of T-cell receptor signaling 2, STS-2, T-cell ubiquitin ligand 1, TULA-1, UBASH3A, STS2