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XK Antibody

Product Specifications

Background

This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx) . Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.

NCBI Gene ID

7504

Swiss Prot

P51811

Accession Number

P51811

Host

Rabbit

Reactivity

Human

Immunogen

This XK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human XK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

XK

NCBI Official Name

Membrane transport protein XK

NCBI Organism

Homo sapiens

Background Reference 01

Miranda, M., et al. Mov. Disord. 22 (9) :1358-1361 (2007)

Background Reference 02

Claperon, A., et al. Brain Res. 1147, 12-24 (2007) :

Background Reference 03

Walker, R.H., et al. Transfusion 47 (2) :299-305 (2007)

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

Membrane transport protein XK, Kell complex 37 kDa component, Kx antigen, XK-related protein 1, XK, XKR1, XRG1

Tested Applications

WB

Protein ID

85700269

Physical Properties

Liquid

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