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HTR1D Antibody

Product Specifications

Background

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

NCBI Gene ID

3352

Swiss Prot

P28221

Accession Number

P28221

Host

Rabbit

Reactivity

Mouse

Immunogen

This HTR1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human HTR1D.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HTR1D

NCBI Official Name

5-hydroxytryptamine receptor 1D

NCBI Organism

Homo sapiens

Background Reference 01

Middeldorp, C.M., et al. Genes Brain Behav. 9 (7) :808-816 (2010)

Background Reference 02

Kiezebrink, K., et al. World J. Biol. Psychiatry 11 (6) :824-833 (2010)

Background Reference 03

Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

Background Reference 04

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Other Product Names

5-hydroxytryptamine receptor 1D, 5-HT-1D, 5-HT1D, Serotonin 1D alpha receptor, 5-HT-1D-alpha, Serotonin receptor 1D, HTR1D, HTR1DA, HTRL

Tested Applications

WB

Protein ID

112819

Physical Properties

Liquid

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