HOXB13 Antibody
Product Specifications
Background
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.
NCBI Gene ID
10481
Swiss Prot
Q92826
Accession Number
Q92826
Host
Rabbit
Reactivity
Mouse
Immunogen
This HOXB13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human HOXB13.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HOXB13
NCBI Official Name
Homeobox protein Hox-B13
NCBI Organism
Homo sapiens
Background Reference 01
McMullin, R.P., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (1) :98-103 (2010)
Background Reference 02
Kim, Y.R., et al. Mol. Cancer 9, 124 (2010) :
Background Reference 03
Norris, J.D., et al. Mol. Cell 36 (3) :405-416 (2009)
Background Reference 04
Goetz, M.P., et al. Clin. Cancer Res. 14 (18) :5864-5868 (2008)
Other Product Names
Homeobox protein Hox-B13, HOXB13
Tested Applications
WB
Protein ID
50403792
Physical Properties
Liquid
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