HOXB13 Antibody

Product Specifications

Background

This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.

NCBI Gene ID

10481

Swiss Prot

Q92826

Accession Number

Q92826

Host

Rabbit

Reactivity

Mouse

Immunogen

This HOXB13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human HOXB13.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HOXB13

NCBI Official Name

Homeobox protein Hox-B13

NCBI Organism

Homo sapiens

Background Reference 01

McMullin, R.P., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (1) :98-103 (2010)

Background Reference 02

Kim, Y.R., et al. Mol. Cancer 9, 124 (2010) :

Background Reference 03

Norris, J.D., et al. Mol. Cell 36 (3) :405-416 (2009)

Background Reference 04

Goetz, M.P., et al. Clin. Cancer Res. 14 (18) :5864-5868 (2008)

Other Product Names

Homeobox protein Hox-B13, HOXB13

Tested Applications

Protein ID

50403792

Physical Properties

Liquid

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