XYLT2 Antibody

Product Specifications

Background

The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.

NCBI Gene ID

64132

Swiss Prot

Q9H1B5

Accession Number

Q9H1B5

Host

Rabbit

Reactivity

Mouse

Immunogen

This XYLT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human XYLT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

97 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

XYLT2

NCBI Official Name

Xylosyltransferase 2

NCBI Organism

Homo sapiens

Background Reference 01

Condac, E., et al. Glycobiology 19 (8) :829-833 (2009)

Background Reference 02

Casanova, J.C., et al. Biochem. Biophys. Res. Commun. 383 (1) :4-10 (2009)

Background Reference 03

Ponighaus, C., et al. Am. J. Hypertens. 22 (4) :432-436 (2009)

Background Reference 04

Ambrosius, M., et al. Clin. Biochem. 42 (1-2), 1-4 (2009) :

Other Product Names

Xylosyltransferase 2, Peptide O-xylosyltransferase 1, Xylosyltransferase II, XT-II, XylT-II, XYLT2, XT2

Tested Applications

Protein ID

126302616

Physical Properties

Liquid

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