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MOCS1 Antibody

Product Specifications

Background

Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants, whose full-length natures have yet to be determined, are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16.

NCBI Gene ID

4337

Swiss Prot

Q9NZB8

Accession Number

Q9NZB8

Host

Rabbit

Reactivity

Human

Immunogen

This MOCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-58 amino acids from the N-terminal region of human MOCS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MOCS1

NCBI Official Name

Molybdenum cofactor biosynthesis protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Sass, J.O., et al. Brain Dev. (2009) In press :

Background Reference 02

Arenas, M., et al. J. Inherit. Metab. Dis. 32 (4) :560-569 (2009)

Background Reference 03

Ichida, K., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1087-1091 (2006) :

Background Reference 04

Macaya, A., et al. Neuropediatrics 36 (6) :389-394 (2005)

Other Product Names

Molybdenum cofactor biosynthesis protein 1, Cell migration-inducing gene 11 protein, Molybdenum cofactor synthesis-step 1 protein A-B, Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein A, Cyclic pyranopterin monophosphate synthase accessory protein, Molybdenum cofactor biosynthesis protein C, MOCS1

Tested Applications

WB

Protein ID

30913216

Physical Properties

Liquid

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