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GNB4 Antibody

Product Specifications

Background

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.

NCBI Gene ID

59345

Swiss Prot

Q9HAV0

Accession Number

Q9HAV0

Host

Rabbit

Reactivity

Human

Immunogen

This GNB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GNB4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Zebrafish, Drosophila, Mouse, Rat, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GNB4

NCBI Official Name

Guanine nucleotide-binding protein subunit beta-4

NCBI Organism

Homo sapiens

Background Reference 01

Riemann, K., et al. Anticancer Res. 29 (4) :1271-1274 (2009)

Background Reference 02

Riemann, K., et al. Pharmacogenet. Genomics 18 (11) :999-1008 (2008)

Background Reference 03

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 04

Rosskopf, D., et al. FEBS Lett. 544 (1-3), 27-32 (2003) :

Other Product Names

Guanine nucleotide-binding protein subunit beta-4, Transducin beta chain 4, GNB4

Tested Applications

WB

Protein ID

22256759

Physical Properties

Liquid

Frequently Asked Questions

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