NCAPG Antibody

Product Specifications

Background

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

NCBI Gene ID

64151

Swiss Prot

Q9BPX3

Accession Number

Q9BPX3

Host

Rabbit

Reactivity

Human

Immunogen

This NCAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the N-terminal region of human NCAPG.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

114 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NCAPG

NCBI Official Name

Condensin complex subunit 3

NCBI Organism

Homo sapiens

Background Reference 01

Okada, Y., et al. Hum. Mol. Genet. 19 (11) :2303-2312 (2010)

Background Reference 02

Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

Background Reference 03

Murphy, L.A., et al. Biochem. Biophys. Res. Commun. 377 (3) :1007-1011 (2008)

Background Reference 04

Gudbjartsson, D.F., et al. Nat. Genet. 40 (5) :609-615 (2008)

Other Product Names

Condensin complex subunit 3, Chromosome-associated protein G, Condensin subunit CAP-G, hCAP-G, Melanoma antigen NY-MEL-3, Non-SMC condensin I complex subunit G, XCAP-G homolog, NCAPG, CAPG, NYMEL3