GPR39 Antibody
Product Specifications
Background
Zn (2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G (q) -alpha and G (12) /G (13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity) .
NCBI Gene ID
2863
Swiss Prot
O43194
Accession Number
O43194
Host
Rabbit
Reactivity
Human
Immunogen
This GPR39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-407 amino acids from the C-terminal region of human GPR39.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GPR39
NCBI Official Name
G-protein coupled receptor 39
NCBI Organism
Homo sapiens
Background Reference 01
Sharir, H., et al. J. Biol. Chem. 285 (34) :26097-26106 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Holst, B., et al. J. Biol. Chem. 285 (6) :3973-3985 (2010)
Background Reference 04
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Other Product Names
G-protein coupled receptor 39, GPR39
Tested Applications
WB
Physical Properties
Liquid
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