RFC1 Antibody
Product Specifications
Background
The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability. [provided by RefSeq].
NCBI Gene ID
5981
Swiss Prot
P35251
Accession Number
P35251
Host
Rabbit
Reactivity
Human
Immunogen
This RFC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human RFC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=60-322
Calculated Molecular Weight
128 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RFC1
NCBI Official Name
Replication factor C subunit 1
NCBI Organism
Homo sapiens
Background Reference 01
Overmeer, R.M., et al. Mol. Cell. Biol. 30 (20) :4828-4839 (2010) Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010) Arora, M., et al. Leukemia 24 (8) :1470-1475 (2010) Galbiatti, A.L., et al. Mol. Biol. Rep. (2010) In pressJugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Other Product Names
Replication factor C subunit 1, Activator 1 140 kDa subunit, A1 140 kDa subunit, Activator 1 large subunit, Activator 1 subunit 1, DNA-binding protein PO-GA, Replication factor C 140 kDa subunit, RF-C 140 kDa subunit, RFC140, Replication factor C large subunit, RFC1, RFC140
Tested Applications
WB
Protein ID
56757608
Physical Properties
Liquid
Curated Selection
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