TRMU Antibody

Product Specifications

Background

This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.

NCBI Gene ID

55687

Swiss Prot

O75648

Accession Number

O75648

Host

Rabbit

Reactivity

Human

Immunogen

This TRMU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-154 amino acids from the Central region of human TRMU.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TRMU

NCBI Official Name

Mitochondrial tRNA-specific 2-thiouridylase 1

NCBI Organism

Homo sapiens

Background Reference 01

Zeharia, A., et al. Am. J. Hum. Genet. 85 (3) :401-407 (2009)

Background Reference 02

Reiling, E., et al. Eur. J. Hum. Genet. 17 (8) :1056-1062 (2009)

Background Reference 03

De Moraes, V.C., et al. Biochem. Biophys. Res. Commun. 381 (2) :210-213 (2009)

Background Reference 04

Otaegui, D., et al. Audiol. Neurootol. 13 (5) :320-327 (2008)

Other Product Names

Mitochondrial tRNA-specific 2-thiouridylase 1, 281-, MTO2 homolog, TRMU, MTU1, TRMT1

Tested Applications

Physical Properties

Liquid

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