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SRP14 Antibody

Product Specifications

Background

Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.

NCBI Gene ID

6727

Swiss Prot

P37108

Accession Number

P37108

Host

Rabbit

Reactivity

Human

Immunogen

This SRP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the Central region of human SRP14.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

SRP14

NCBI Official Name

Signal recognition particle 14 kDa protein

NCBI Organism

Homo sapiens

Background Reference 01

Mary, C., et al. RNA 16 (5) :969-979 (2010)

Background Reference 02

Lakkaraju, A.K., et al. Cell 133 (3) :440-451 (2008)

Background Reference 03

Yoshida, M., et al. Mol. Pharmacol. 73 (3) :987-994 (2008)

Background Reference 04

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Other Product Names

Signal recognition particle 14 kDa protein, SRP14, 18 kDa Alu RNA-binding protein, SRP14

Tested Applications

WB

Protein ID

116242801

Physical Properties

Liquid

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