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SPANXE Antibody

Product Specifications

Background

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that contains a consensus nuclear localization signal but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined.

NCBI Gene ID

64663

Swiss Prot

Q8TAD1

Accession Number

Q8TAD1

Host

Rabbit

Reactivity

Human

Immunogen

This SPANXE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the Central region of human SPANXE.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-307

Calculated Molecular Weight

11 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SPANXE

NCBI Official Name

Sperm protein associated with the nucleus on the X chromosome E

NCBI Organism

Homo sapiens

Background Reference 01

Hansen, S., et al. Syst Biol Reprod Med 55, 18-26 (2010) :

Background Reference 02

Kouprina, N., et al. Genome Res. 15 (11) :1477-1486 (2005)

Background Reference 03

Zendman, A.J., et al. Gene 309 (2) :125-133 (2003)

Background Reference 04

Westbrook, V.A., et al. Biol. Reprod. 64 (1) :345-358 (2001)

Other Product Names

Sperm protein associated with the nucleus on the X chromosome E, Nuclear-associated protein SPAN-Xe, SPANX-E, SPANX family member E, SPANXE

Tested Applications

WB

Protein ID

85543354

Physical Properties

Liquid

Curated Selection

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