TIMM50 Antibody

Product Specifications

Background

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.

NCBI Gene ID

92609

Swiss Prot

Q3ZCQ8

Accession Number

Q3ZCQ8

Host

Rabbit

Reactivity

Human

Immunogen

This TIMM50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-104 amino acids from the N-terminal region of human TIMM50.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TIMM50

NCBI Official Name

Mitochondrial import inner membrane translocase subunit TIM50

NCBI Organism

Homo sapiens

Background Reference 01

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 02

Xu, H., et al. BMC Cell Biol. (1), 29 (2005) :

Background Reference 03

Guo, Y., et al. J. Biol. Chem. 279 (23) :24813-24825 (2004)

Background Reference 04

Yuryev, A., et al. Genomics 81 (2) :112-125 (2003)

Other Product Names

Mitochondrial import inner membrane translocase subunit TIM50, TIMM50, TIM50

Tested Applications

Protein ID

83305924

Physical Properties

Liquid

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