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LYPLA1 Antibody

Product Specifications

Background

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.

NCBI Gene ID

10434

Swiss Prot

O75608

Accession Number

O75608

Host

Rabbit

Reactivity

Human

Immunogen

This LYPLA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the Central region of human LYPLA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LYPLA1

NCBI Official Name

Acyl-protein thioesterase 1

NCBI Organism

Homo sapiens

Background Reference 01

Satou, M., et al. Endocrinology 151 (10) :4765-4775 (2010)

Background Reference 02

Dekker, F.J., et al. Nat. Chem. Biol. 6 (6) :449-456 (2010)

Background Reference 03

Hirano, T., et al. Biochim. Biophys. Acta 1791 (8) :797-805 (2009)

Background Reference 04

Siegel, G., et al. Nat. Cell Biol. 11 (6) :705-716 (2009)

Other Product Names

Acyl-protein thioesterase 1, APT-1, hAPT1, 312-, Lysophospholipase 1, Lysophospholipase I, LPL-I, LysoPLA I, LYPLA1, APT1, LPL1

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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