RREB1 Antibody
Product Specifications
Background
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene.
NCBI Gene ID
6239
Swiss Prot
Q92766
Accession Number
Q92766
Host
Rabbit
Reactivity
Human
Immunogen
This RREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1398-1424 amino acids from the C-terminal region of human RREB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=60-287
Calculated Molecular Weight
181 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RREB1
NCBI Official Name
Ras-responsive element-binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Neale, B.M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (16) :7395-7400 (2010)
Background Reference 03
Milon, B.C., et al. Prostate 70 (3) :288-296 (2010)
Background Reference 04
Flajollet, S., et al. J. Immunol. 183 (11) :6948-6959 (2009)
Other Product Names
Ras-responsive element-binding protein 1, RREB-1, Finger protein in nuclear bodies, Raf-responsive zinc finger protein LZ321, Zinc finger motif enhancer-binding protein 1, Zep-1, RREB1, FINB
Tested Applications
WB
Protein ID
152031673
Physical Properties
Liquid
Curated Selection
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