PSG4 Antibody
Product Specifications
Background
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]) . For additional general information about the PSG gene family, see PSG1 (MIM 176390) .
NCBI Gene ID
5672
Swiss Prot
Q00888
Accession Number
Q00888
Host
Rabbit
Reactivity
Human
Immunogen
This PSG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-100 amino acids from the N-terminal region of human PSG4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=60-276
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PSG4
NCBI Official Name
Pregnancy-specific beta-1-glycoprotein 4
NCBI Organism
Homo sapiens
Background Reference 01
Kimoto, Y. Mol. Gen. Genet. 258 (3) :233-239 (1998)
Background Reference 02
Teglund, S., et al. Biochem. Biophys. Res. Commun. 211 (2) :656-664 (1995)
Background Reference 03
Teglund, S., et al. Genomics 23 (3) :669-684 (1994)
Background Reference 04
Olsen, A., et al. Genomics 23 (3) :659-668 (1994)
Other Product Names
Pregnancy-specific beta-1-glycoprotein 4, PS-beta-G-4, PSBG-4, Pregnancy-specific glycoprotein 4, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9, PSBG-9, Pregnancy-specific glycoprotein 9, PSG4, CGM4, PSG9
Tested Applications
WB
Protein ID
313104197
Physical Properties
Liquid
Curated Selection
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