PAIP1 Antibody

Product Specifications

Background

The protein encoded by this gene interacts with poly (A) -binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

NCBI Gene ID

10605

Swiss Prot

Q9H074

Accession Number

Q9H074

Host

Rabbit

Reactivity

Human

Immunogen

This PAIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human PAIP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PAIP1

NCBI Official Name

Polyadenylate-binding protein-interacting protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Kanaan, A.S., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 65 (PT 10), 1060-1064 (2009) :

Background Reference 02

Martineau, Y., et al. Mol. Cell. Biol. 28 (21) :6658-6667 (2008)

Background Reference 03

Fortna, A., et al. PLoS Biol. (7), E207 (2004) :

Background Reference 04

Roy, G., et al. Mol. Cell. Biol. 22 (11) :3769-3782 (2002)

Other Product Names

Polyadenylate-binding protein-interacting protein 1, PABP-interacting protein 1, PAIP-1, Poly (A) -binding protein-interacting protein 1, PAIP1

Tested Applications

Protein ID

46397025

Physical Properties

Liquid

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