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TBX4 Antibody

Product Specifications

Background

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.

NCBI Gene ID

9496

Swiss Prot

P57082

Accession Number

P57082

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TBX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-129 amino acids from the N-terminal region of human TBX4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Rat, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TBX4

NCBI Official Name

T-box transcription factor TBX4

NCBI Organism

Homo sapiens

Background Reference 01

Kim, J.J., et al. J. Hum. Genet. 55 (1) :27-31 (2010)

Background Reference 02

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 03

Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

Background Reference 04

Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

Other Product Names

T-box transcription factor TBX4, T-box protein 4, TBX4

Tested Applications

WB

Protein ID

51338786

Physical Properties

Liquid

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