RNASE2 Antibody

Product Specifications

Background

This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.

NCBI Gene ID

6036

Swiss Prot

P10153

Accession Number

P10153

Host

Rabbit

Reactivity

Human

Immunogen

This RNASE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the C-terminal region of human RNASE2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

18 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RNASE2

NCBI Official Name

Non-secretory ribonuclease

NCBI Organism

Homo sapiens

Background Reference 01

McGovern, D.P., et al. Hum. Mol. Genet. 19 (17) :3468-3476 (2010)

Background Reference 02

Plager, D.A., et al. J. Immunol. 183 (6) :4013-4020 (2009)

Background Reference 03

Wang, H.Y., et al. J. Cell. Biochem. 106 (2) :317-326 (2009)

Background Reference 04

Ueki, M., et al. Cell Biochem. Funct. 26 (6) :718-722 (2008)

Other Product Names

Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US, RNASE2, EDN, RNS2

Tested Applications

Protein ID

133168

Physical Properties

Liquid

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