PODXL Antibody

Product Specifications

Background

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

NCBI Gene ID

5420

Swiss Prot

O00592

Accession Number

O00592

Host

Rabbit

Reactivity

Human

Immunogen

This PODXL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human PODXL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PODXL

NCBI Official Name

Podocalyxin

NCBI Organism

Homo sapiens

Background Reference 01

Schopperle, W.M., et al. Biochem. Biophys. Res. Commun. 398 (3) :372-376 (2010)

Background Reference 02

Hsu, Y.H., et al. Am. J. Pathol. 176 (6) :3050-3061 (2010)

Background Reference 03

Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :

Background Reference 04

Drossopoulou, G.I., et al. Am. J. Physiol. Renal Physiol. 297 (3), F594-F603 (2009) :

Other Product Names

Podocalyxin, GCTM-2 antigen, Gp200, Podocalyxin-like protein 1, PC, PCLP-1, PODXL, PCLP, PCLP1

Tested Applications

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS7164297 Inquire

H Antibody

Ask

View Details

PVT63976 2 µg

PLV3-CMV-Plin5-3xFLAG-CopGFP-Puro Plasmid

Ask

View Details

MBS2707940-01 24 Strip Well

Rat Calcitonin Gene Related Peptide (CGRP) CLIA Kit

Ask

View Details

MBS2707940-02 48 Well

Rat Calcitonin Gene Related Peptide (CGRP) CLIA Kit

Ask

View Details

MBS2707940-03 96 Well

Rat Calcitonin Gene Related Peptide (CGRP) CLIA Kit

Ask

View Details

MBS2707940-04 5x 96 Well

Rat Calcitonin Gene Related Peptide (CGRP) CLIA Kit

Ask

View Details