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PTCRA Antibody

Product Specifications

Background

In immature T cells the T-cell receptor beta-chain gene (TCRB; MIM 186930) is rearranged and expressed before the TCRA (MIM 186880) chain. At this early stage, TCRB can associate with the pre-T-cell receptor alpha chain (PTCRA) . The PTCRA, together with TCRB and the CD3 complex (see MIM 186740), minimally make up the pre-T cell receptor (pre-TCR), which regulates early T cell development.

NCBI Gene ID

171558

Swiss Prot

Q6ISU1

Accession Number

Q6ISU1

Host

Rabbit

Reactivity

Human

Immunogen

This PTCRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human PTCRA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PTCRA

NCBI Official Name

Pre T-cell antigen receptor alpha

NCBI Organism

Homo sapiens

Background Reference 01

Velez, D.R., et al. Am. J. Obstet. Gynecol. 200 (2), 209 (2009) :

Background Reference 02

Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :

Background Reference 03

Velez, D.R., et al. PLoS ONE (9), E3283 (2008) :

Background Reference 04

Navarro, M.N., et al. Blood 110 (13) :4331-4340 (2007)

Other Product Names

Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA

Tested Applications

WB

Protein ID

74736631

Physical Properties

Liquid

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