APBA3 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.

NCBI Gene ID

9546

Swiss Prot

O96018

Accession Number

O96018

Host

Rabbit

Reactivity

Human

Immunogen

This APBA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-327 amino acids from the Central region of human APBA3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

APBA3

NCBI Official Name

Amyloid beta A4 precursor protein-binding family A member 3

NCBI Organism

Homo sapiens

Background Reference 01

Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010) Swistowski, A., et al. J. Neurosci. 29 (50) :15703-15712 (2009) Sakamoto, T., et al. J. Biol. Chem. 284 (44) :30350-30359 (2009) Han, J., et al. J. Cell. Sci. 121 (PT 13), 2217-2223 (2008) Shrivastava-Ranjan, P., et al. Mol. Biol. Cell 19 (1) :51-64 (2008)

Other Product Names

Amyloid beta A4 precursor protein-binding family A member 3, Adapter protein X11gamma, Neuron-specific X11L2 protein, Neuronal Munc18-1-interacting protein 3, Mint-3, APBA3, MINT3, X11L2