GAS2 Antibody
Product Specifications
Background
The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.
NCBI Gene ID
2620
Swiss Prot
O43903
Accession Number
O43903
Host
Rabbit
Reactivity
Human
Immunogen
This GAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-94 amino acids from the N-terminal region of human GAS2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GAS2
NCBI Official Name
Growth arrest-specific protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Huang, W., et al. Mol. Cell. Biol. 30 (19) :4575-4594 (2010)
Background Reference 02
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 03
Benetti, R., et al. J. Biol. Chem. 280 (23) :22070-22080 (2005)
Background Reference 04
Tsutsumi, S., et al. Am. J. Hum. Genet. 74 (6) :1255-1261 (2004)
Other Product Names
Growth arrest-specific protein 2, GAS-2, GAS2
Tested Applications
WB
Physical Properties
Liquid
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