G2E3 Antibody

Product Specifications

Background

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.

NCBI Gene ID

55632

Swiss Prot

Q7L622

Accession Number

Q7L622

Host

Rabbit

Reactivity

Human

Immunogen

This G2E3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-252 amino acids from the Central region of human G2E3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

81 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

G2E3

NCBI Official Name

G2/M phase-specific E3 ubiquitin-protein ligase

NCBI Organism

Homo sapiens

Background Reference 01

Brooks, W.S., et al. J. Biol. Chem. 283 (32) :22304-22315 (2008)

Background Reference 02

Brooks, W.S., et al. Exp. Cell Res. 313 (4) :665-676 (2007)

Background Reference 03

Lehner, B., et al. Genomics 83 (1) :153-167 (2004)

Background Reference 04

Crawford, D.F., et al. J. Biol. Chem. 276 (40) :37166-37177 (2001)

Other Product Names

G2/M phase-specific E3 ubiquitin-protein ligase, 632-, G2E3, KIAA1333

Tested Applications

Protein ID

74738611

Physical Properties

Liquid

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