NPL Antibody

Product Specifications

Background

N-acetylneuraminate pyruvate lyase (EC 4.1.3.3) controls the cellular concentration of sialic acid by catalyzing the conversion of sialic acid into acylmannosamines and pyruvate (Wu et al., 2005 [PubMed 16147865]) .

NCBI Gene ID

80896

Swiss Prot

Q9BXD5

Accession Number

Q9BXD5

Host

Rabbit

Reactivity

Human

Immunogen

This NPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human NPL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NPL

NCBI Official Name

N-acetylneuraminate lyase

NCBI Organism

Homo sapiens

Background Reference 01

Chu, H.Y., et al.Mol Model 15 (3) :323-328 (2009)

Background Reference 02

Wu, M., et al. DNA Seq. 16 (2) :137-142 (2005)

Background Reference 03

Traving, C., et al. Eur. J. Biochem. 268 (24) :6473-6486 (2001)

Background Reference 04

Sood, R., et al. Genomics 73 (2) :211-222 (2001)

Other Product Names

N-acetylneuraminate lyase, NALase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialate-pyruvate lyase, Sialic acid aldolase, Sialic acid lyase, NPL, C1orf13