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Mouse Sgk1 Antibody

Product Specifications

Background

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. This enzyme is activated by protein phosphorylation and degraded via the ubiquitination and proteasome pathway. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 12.

NCBI Gene ID

20393

Swiss Prot

Q9WVC6

Accession Number

Q9WVC6

Host

Rabbit

Reactivity

Human

Immunogen

This Mouse Sgk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of mouse Sgk1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Sgk1

NCBI Official Name

Serine/threonine-protein kinase Sgk1

NCBI Organism

Mus musculus

Background Reference 01

Gao, D., et al. Mol. Cell 39 (5) :797-808 (2010)

Background Reference 02

Catela, C., et al. Dev. Dyn. 239 (8) :2149-2160 (2010)

Background Reference 03

Hallows, K.R., et al. J. Biol. Chem. 285 (28) :21671-21678 (2010)

Background Reference 04

Kaji, T., et al. Front Biosci (Elite Ed) 2, 1355-1361 (2010) :

Other Product Names

Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1, Sgk1, Sgk

Tested Applications

WB

Physical Properties

Liquid

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