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VAPB Antibody

Product Specifications

Background

The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.

NCBI Gene ID

9217

Swiss Prot

O95292

Accession Number

O95292

Host

Rabbit

Reactivity

Human

Immunogen

This VAPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-200 amino acids from the C-terminal region of human VAPB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

VAPB

NCBI Official Name

Vesicle-associated membrane protein-associated protein B/C

NCBI Organism

Homo sapiens

Background Reference 01

Millecamps, S., et al. J. Med. Genet. 47 (8) :554-560 (2010)

Background Reference 02

Langou, K., et al. J. Neurochem. 114 (3) :795-809 (2010)

Background Reference 03

Tsai, C.P., et al. Neurobiol. Aging (2010) In press :

Background Reference 04

Nachreiner, T., et al. Biochem. Biophys. Res. Commun. 394 (3) :703-708 (2010)

Other Product Names

Vesicle-associated membrane protein-associated protein B/C, VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C, VAPB

Tested Applications

WB

Physical Properties

Liquid

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