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PLA2G3 Antibody

Product Specifications

Background

PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2; EC 3.1.1.4) proteins. These Ca (2+) -dependent lipolytic enzymes have a conserved Ca (2+) -binding loop and a his-asp dyad in the catalytic site (Murakami et al., 2003 [PubMed 12522102]) .

NCBI Gene ID

50487

Swiss Prot

Q9NZ20

Accession Number

Q9NZ20

Host

Rabbit

Reactivity

Human

Immunogen

This PLA2G3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-474 amino acids from the C-terminal region of human PLA2G3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PLA2G3

NCBI Official Name

Group 3 secretory phospholipase A2

NCBI Organism

Homo sapiens

Background Reference 01

Wang, G., et al. J. Neurochem. 114 (4) :1039-1048 (2010) Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010) Segat, L., et al. Vaccine 28 (10) :2201-2206 (2010) Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010) Sato, H., et al. Biochem. J. 421 (1) :17-27 (2009)

Other Product Names

Group 3 secretory phospholipase A2, Group III secretory phospholipase A2, GIII sPLA2, sPLA2-III, Phosphatidylcholine 2-acylhydrolase 3, PLA2G3

Tested Applications

WB

Protein ID

317373314

Physical Properties

Liquid

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