PLA2G3 Antibody
Product Specifications
Background
PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2; EC 3.1.1.4) proteins. These Ca (2+) -dependent lipolytic enzymes have a conserved Ca (2+) -binding loop and a his-asp dyad in the catalytic site (Murakami et al., 2003 [PubMed 12522102]) .
NCBI Gene ID
50487
Swiss Prot
Q9NZ20
Accession Number
Q9NZ20
Host
Rabbit
Reactivity
Human
Immunogen
This PLA2G3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-474 amino acids from the C-terminal region of human PLA2G3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PLA2G3
NCBI Official Name
Group 3 secretory phospholipase A2
NCBI Organism
Homo sapiens
Background Reference 01
Wang, G., et al. J. Neurochem. 114 (4) :1039-1048 (2010) Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010) Segat, L., et al. Vaccine 28 (10) :2201-2206 (2010) Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010) Sato, H., et al. Biochem. J. 421 (1) :17-27 (2009)
Other Product Names
Group 3 secretory phospholipase A2, Group III secretory phospholipase A2, GIII sPLA2, sPLA2-III, Phosphatidylcholine 2-acylhydrolase 3, PLA2G3
Tested Applications
WB
Protein ID
317373314
Physical Properties
Liquid
Curated Selection
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