RARRES3 Antibody

Product Specifications

Background

Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.

NCBI Gene ID

5920

Swiss Prot

Q9UL19

Accession Number

Q9UL19

Host

Rabbit

Reactivity

Human

Immunogen

This RARRES3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the Central region of human RARRES3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

18 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RARRES3

NCBI Official Name

Retinoic acid receptor responder protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Silva, L.K., et al. Eur. J. Hum. Genet. 18 (11) :1221-1227 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Uyama, T., et al. Biochim. Biophys. Acta 1791 (12) :1114-1124 (2009)

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Retinoic acid receptor responder protein 3, 311-, HRAS-like suppressor 4, HRSL4, RAR-responsive protein TIG3, Retinoid-inducible gene 1 protein, Tazarotene-induced gene 3 protein, RARRES3, RIG1, TIG3