ARHGAP1 Antibody

Product Specifications

Background

GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.

NCBI Gene ID

392

Swiss Prot

Q07960

Accession Number

Q07960

Host

Rabbit

Reactivity

Human

Immunogen

This ARHGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human ARHGAP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARHGAP1

NCBI Official Name

Rho GTPase-activating protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Takefuji, M., et al. J. Hum. Genet. 55 (1) :42-49 (2010)

Background Reference 02

Rivadeneira, F., et al. Nat. Genet. 41 (11) :1199-1206 (2009)

Background Reference 03

Mori, K., et al. J. Biol. Chem. 284 (8) :5067-5076 (2009)

Background Reference 04

Scholz, R.P., et al. J. Cell. Sci. 122 (PT 1), 92-102 (2009) :

Other Product Names

Rho GTPase-activating protein 1, CDC42 GTPase-activating protein, GTPase-activating protein rhoOGAP, Rho-related small GTPase protein activator, Rho-type GTPase-activating protein 1, p50-RhoGAP, ARHGAP1, CDC42GAP, RHOGAP1