RALGDS Antibody

Product Specifications

Background

Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.

NCBI Gene ID

5900

Swiss Prot

Q12967

Accession Number

Q12967

Host

Rabbit

Reactivity

Human

Immunogen

This RALGDS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the Central region of human RALGDS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

101 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RALGDS

NCBI Official Name

Ral guanine nucleotide dissociation stimulator

NCBI Organism

Homo sapiens

Background Reference 01

Fuentes, G., et al. Trends Biochem. Sci. 34 (11) :533-539 (2009)

Background Reference 02

Maehama, T., et al. J. Biol. Chem. 283 (50) :35053-35059 (2008)

Background Reference 03

Rondaij, M.G., et al. Blood 112 (1) :56-63 (2008)

Background Reference 04

Omholt, K., et al. Melanoma Res. 17 (6) :410-412 (2007)

Other Product Names

Ral guanine nucleotide dissociation stimulator, RalGDS, Ral guanine nucleotide exchange factor, RalGEF, RALGDS, KIAA1308, RGF

Tested Applications

Protein ID

14549162

Physical Properties

Liquid

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