SLC22A2 Antibody
Product Specifications
Background
SLC22A2 mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4- (dimethylamino) -styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.
NCBI Gene ID
6582
Swiss Prot
O15244
Accession Number
O15244
Host
Rabbit
Reactivity
Human
Immunogen
This SLC22A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 514-541 amino acids from the C-terminal region of human SLC22A2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=60-152
Calculated Molecular Weight
63 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SLC22A2
NCBI Official Name
Solute carrier family 22 member 2
NCBI Organism
Homo sapiens
Other Product Names
Solute carrier family 22 member 2, Organic cation transporter 2, hOCT2, SLC22A2, OCT2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6317646-01 0.1 mL
LY6G6F, NT (LY6G6F, C6orf21, G6F, LY6G6D, NG32, Lymphocyte antigen 6 complex locus protein G6f) (MaxLight 750)
Ask
View Details MBS6317646-02 5x 0.1 mL
LY6G6F, NT (LY6G6F, C6orf21, G6F, LY6G6D, NG32, Lymphocyte antigen 6 complex locus protein G6f) (MaxLight 750)
Ask
View Details 