STX4 Antibody

Product Specifications

Background

Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity) . May also play a role in docking of synaptic vesicles at presynaptic active zones.

NCBI Gene ID

6810

Swiss Prot

Q12846

Accession Number

Q12846

Host

Rabbit

Reactivity

Human

Immunogen

This STX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the Central region of human STX4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

STX4

NCBI Official Name

Syntaxin-4

NCBI Organism

Homo sapiens

Background Reference 01

Evesson, F.J., et al. J. Biol. Chem. 285 (37) :28529-28539 (2010)

Background Reference 02

Kennedy, M.J., et al. Cell 141 (3) :524-535 (2010)

Background Reference 03

Brochetta, C., et al. Biochim. Biophys. Acta 1783 (10) :1781-1791 (2008)

Background Reference 04

Cooper, G.M., et al. Blood 112 (4) :1022-1027 (2008)

Other Product Names

Syntaxin-4, Renal carcinoma antigen NY-REN-31, STX4, STX4A

Tested Applications

Protein ID

3041737

Physical Properties

Liquid

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