TPD52L1 Antibody

Product Specifications

Background

This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined.

NCBI Gene ID

7164

Swiss Prot

Q16890

Accession Number

Q16890

Host

Rabbit

Reactivity

Mouse

Immunogen

This TPD52L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human TPD52L1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TPD52L1

NCBI Official Name

Tumor protein D53

NCBI Organism

Homo sapiens

Background Reference 01

Barbaric, D., et al. Leuk. Res. 30 (11) :1355-1363 (2006)

Background Reference 02

Cao, Q., et al. Biochem. Biophys. Res. Commun. 344 (3) :798-806 (2006)

Background Reference 03

Boutros, R., et al. Exp. Cell Res. 310 (1) :152-165 (2005)

Background Reference 04

Cho, S., et al. J. Biol. Chem. 279 (16) :16050-16056 (2004)

Other Product Names

Tumor protein D53, hD53, Tumor protein D52-like 1, TPD52L1

Tested Applications

Protein ID

12585368

Physical Properties

Liquid

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