RPA4 Antibody
Product Specifications
Background
This gene encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.
NCBI Gene ID
29935
Swiss Prot
Q13156
Accession Number
Q13156
Host
Rabbit
Reactivity
Human
Immunogen
This RPA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-261 amino acids from the C-terminal region of human RPA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RPA4
NCBI Official Name
Replication protein A 30 kDa subunit
NCBI Organism
Homo sapiens
Background Reference 01
Kemp, M.G., et al. J. Biol. Chem. 285 (7) :4788-4797 (2010)
Background Reference 02
Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)
Background Reference 03
Haring, S.J., et al. Nucleic Acids Res. 38 (3) :846-858 (2010)
Background Reference 04
Shen, M., et al. Environ. Mol. Mutagen. 50 (4) :285-290 (2009)
Other Product Names
Replication protein A 30 kDa subunit, RP-A p30, Replication factor A protein 4, RF-A protein 4, RPA4
Tested Applications
WB
Protein ID
14917036
Physical Properties
Liquid
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