CLEC6A Antibody
Product Specifications
Background
Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004 [PubMed 15175046]) .
NCBI Gene ID
93978
Swiss Prot
Q6EIG7
Accession Number
Q6EIG7
Host
Rabbit
Reactivity
Human
Immunogen
This CLEC6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-163 amino acids from the C-terminal region of human CLEC6A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CLEC6A
NCBI Official Name
C-type lectin domain family 6 member A
NCBI Organism
Homo sapiens
Background Reference 01
Gavino, A.C., et al. Exp. Dermatol. 14 (4) :281-288 (2005)
Background Reference 02
Flornes, L.M., et al. Immunogenetics 56 (7) :506-517 (2004)
Background Reference 03
Kanazawa, N., et al. J. Invest. Dermatol. 122 (6) :1522-1524 (2004)
Other Product Names
C-type lectin domain family 6 member A, C-type lectin superfamily member 10, Dendritic cell-associated C-type lectin 2, DC-associated C-type lectin 2, Dectin-2, CLEC6A, CLECSF10, DECTIN2
Tested Applications
WB
Protein ID
59797926
Physical Properties
Liquid
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