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FBXO22 Antibody

Product Specifications

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene.

NCBI Gene ID

26263

Swiss Prot

Q8NEZ5

Accession Number

Q8NEZ5

Host

Rabbit

Reactivity

Mouse

Immunogen

This FBXO22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the C-terminal region of human FBXO22.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FBXO22

NCBI Official Name

F-box only protein 22

NCBI Organism

Homo sapiens

Background Reference 01

Borziak, K., et al. Bioinformatics 23 (19) :2518-2521 (2007)

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Winston, J.T., et al. Curr. Biol. 9 (20) :1180-1182 (1999)

Background Reference 04

Cenciarelli, C., et al. Curr. Biol. 9 (20) :1177-1179 (1999)

Other Product Names

F-box only protein 22, F-box protein FBX22p44, FBXO22, FBX22

Tested Applications

WB

Protein ID

30580428

Physical Properties

Liquid

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