AKR1E2 Antibody

Product Specifications

Background

AKR1E2 catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones (By similarity) . Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro) .

NCBI Gene ID

83592

Swiss Prot

Q96JD6

Accession Number

Q96JD6

Host

Rabbit

Reactivity

Human

Immunogen

This AKR1E2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human AKR1E2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AKR1E2

NCBI Official Name

1,5-anhydro-D-fructose reductase

NCBI Organism

Homo sapiens

Background Reference 01

Clancy, R.M., et al. Arthritis Rheum. 62 (11) :3415-3424 (2010)

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

Background Reference 04

Azuma, Y., et al. Mol. Hum. Reprod. 10 (7) :527-533 (2004)

Other Product Names

5-anhydro-D-fructose reductase, AF reductase, Aldo-keto reductase family 1 member C-like protein 2, Aldo-keto reductase family 1 member E2, LoopADR, Testis-specific protein, hTSP, AKR1E2, AKR1CL2, AKRDC1