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PPP1R1C Antibody

Product Specifications

Background

Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]) .[supplied by OMIM].

NCBI Gene ID

151242

Swiss Prot

Q8WVI7

Accession Number

Q8WVI7

Host

Rabbit

Reactivity

Mouse

Immunogen

This PPP1R1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-76 amino acids from the N-terminal region of human PPP1R1C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

12 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PPP1R1C

NCBI Official Name

Protein phosphatase 1 regulatory subunit 1C

NCBI Organism

Homo sapiens

Background Reference 01

Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. (2010) In press :

Background Reference 02

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 03

Zeng, Q., et al. Biotechnol. Appl. Biochem. 54 (4) :231-238 (2009)

Background Reference 04

Wang, X., et al. J. Biol. Chem. 283 (18) :12076-12084 (2008)

Other Product Names

Protein phosphatase 1 regulatory subunit 1C, Inhibitor-5 of protein phosphatase 1, IPP5, PPP1R1C

Tested Applications

WB

Protein ID

74730857

Physical Properties

Liquid

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