SEPT6 Antibody
Product Specifications
Background
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
NCBI Gene ID
23157
Swiss Prot
Q14141
Accession Number
Q14141
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This SEPT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human SEPT6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SEPT6
NCBI Official Name
Septin-6
NCBI Organism
Homo sapiens
Background Reference 01
Ding, X., et al. J. Biochem. Mol. Biol. 40 (6) :973-978 (2007)
Background Reference 02
Sirajuddin, M., et al. Nature 449 (7160) :311-315 (2007)
Background Reference 03
Kremer, B.E., et al. Cell 130 (5) :837-850 (2007)
Background Reference 04
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Other Product Names
Septin-6, SEPT6, KIAA0128, SEP2
Tested Applications
WB
Protein ID
20178343
Physical Properties
Liquid
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